MEMO 4D TM
MEMO 4DTMSEMI-RIGID ANNULOPLASTY RING
Reshaping Mitral Repair
Designed to support a comprehensive range of techniques1
With its innovative chordal guiding system, it turns artificial chordae replacement into standard procedure2
CC-MK-00032 B
Features
Design elements
UNIQUE RANGE OF SIZES*
Up to size 42 mm to treat large annuli.
A complete range of sizes to meet a size-specific repair principle. The 42 mm size is unique to Memo 4DTM.
PROGRESSIVE INCREASE OF THE ANTEROPOSTERIOR DIAMETER
The progressive increase of the anteroposterior diameter of Memo 4D, from size 34 to size 42, helps accommodate excess leaflet tissue, while reducing the risk of systolic anterior motion (SAM).3
EXCLUSIVE GRADUAL SADDLE SHAPING
The anterior saddle shape is gradually enhanced from size 34 to size 42.
It is designed to restore the physiological geometry in enlarged annuli that have lost their three-dimensional profile.4
STABILITY AND SUPPORT
The right balance of rigidity and flexibility to cover a comprehensive range of mitral valve repair needs.1
The natural annular dynamics of the Memo platform is clinically proven and acknowledged.5,6
THREE LAYER STRUCTURE
Oval silicone sheath - Ease-of-implant with an adequate annular fit.
Nitinol cell structure - Accommodates the diastolic phase and provides consistent recovery of the natural systolic profile.5,6
Carbofilm Coating - Reduces inflammatory reaction favoring a gentle endothelialization.7,8
OPTIMIZED HEMODYNAMICS5,6,9
Truly physiological three-dimensional motion of the mitral annulus with a natural anterior/posterior to lateral/lateral relationship to maximize blood flow5, even five years after implantation.6,10
Ease-of-Implant
THE “SLIM FIT” RING DESIGNED TO FIT OPTIMALLY TO THE PATIENT ANNULUS
Wide, streamlined silicone filler facilitates suturability
Designed to optimally fit to the mitral annulus
A FULLY VERSATILE HOLDER
Chordal Window - Neochordae can pass through the aperture
One-Cut Removal - Single cut to unhook the whole holder
DESIGNED TO FACILITATE MICS APPROACH
Low-profile holder
Ultra-slim template with two handles
RECHORD SYSTEM
ReChord System - A chordal sizing system that aims to standardize neochordae implantation without the need for physical measurement.11,12
A series of loops in the posterior region act as temporary reference elements for easier length sizing of chords for both anterior and posterior repair.
The innovative system promotes standardized chord implantation, offering a reproducible technique while accelerating procedure times.11,12
“The chordal guiding system markedly reduces the time of the procedure by facilitating sizing and knotting.” 13
* among semi-rigid annuloplasty rings
Clinical Evidence
Performance
Memo 4D is the most recent device of the Memo annuloplasty ring family. Memo 3D clinical data can be used as reference for Memo 4D.
TRULY 3D MOTION
The truly 3D motion of the ring during the cardiac cycle preserves the non-planar saddle shape geometry of the annulus. Recent clinical data have demonstrated that Memo 3D is able to accommodate the physiological saddle shape of the mitral annulus throughout the cardiac cycle upon implantation.5,6
SYSTOLIC REMODELING AND DIASTOLIC DYNAMICS CONCEPT
Truly three-dimensional motion of the mitral annulus with a anterior/posterior to lateral/lateral relationship to maximize blood flow5,6 even more than five years after implantation.10
Systolic remodeling optimized coaptation and reduced stress5
Diastolic dynamics optimized hemodynamics6
References
Nasso et al.
Three-Year Results of Repaired Barlow Mitral Valves via Right Minithoracotomy versus Median Sternotomy in a Randomized Trial.
Cardiology 2014;128:97–105
Glauber et al.
Minimally invasive mitral valve repair using a semi-rigid annuloplasty ring with a new chordal sizing system: the Memo 3D ReChord.
Ann Cardiothorac Surg 2015;4(3):298-300.
Adams et al.
Large Annuloplasty Rings Facilitate Mitral Valve Repair in Barlow’s Disease
Ann Thorac Surg 2006;82:2096–10
Lee et al.
Quantitative Analysis of Mitral Valve Morphology in Mitral Valve Prolapse With Real-Time 3-Dimensional Echocardiography Importance of Annular Saddle Shape in the Pathogenesis of Mitral Regurgitation.
Circulation 2013;127:832-841
Nishi et al.
Annular dynamics of Memo 3D annuloplasty ring evaluated by 3D transesophageal echocardiography.
General Thoracic and Cardiovascular Surgery, 2018 Apr;66(4):214-219
Ryomoto et al.
Physiological mitral annular dynamics preserved after ring annuloplasty in mid-term period.
Gen Thorac Cardiovasc Surg (2017) 65:627–632
Della Barbera et al.
Sovering annuloplasty rings: Experimental pathology in the sheep model.
Cardiovascular Pathology 14 (2005) 96–103
Bruno et al.
Early Clinical Experience and Echocardiographic Results With a New Semirigid Mitral Annuloplasty Ring: The Sorin Memo 3D.
Ann Thorac Surg 2009;88:1492– 8
Fattouch et al.
A Comparison of 2 Mitral Annuloplasty Rings for Severe Ischemic Mitral Regurgitation: Clinical and Echocardiographic Outcomes.
Semin Thoracic Surg28:261–268 I 2016
Santarpino G et al.
First-in-man implantation of a Sorin MEMO 3D ring: Mitral annular flexibility is still preserved at 5 years of follow-up!
Int J Cardiol. 2012 Dec 14
Wan et al.
Mitral valve repair using a semirigid ring: Patient selection and early outcomes.
Asian Cardiovascular & Thoracic Annals 0(0) 1–6 The Author(s) 2016
Prinzing et al.
Initial Experience With a New Mitral Ring Designed to Simplify Length Determination of Neochords.
Ann Thorac Surg 2018;105:1784–9
G. Szabó et al.
The Novel Livanova 3D Rechord Semirigid Ring Facilitates Mitral Valve Repair With Artificial Chords: A Matched Pair Analysis.
Thorac cardiovasc Surg 2018; 66(S 01): S1-S110
Technical claims supported by CORCYM data on file.
Safety Information
important SAFETY INFORMATION DOCUMENT
Manufactured by:
Corcym S.r.l.
Via Crescentino sn
13040 Saluggia (VC) Italy
Теl: +39 0161 1640001
Corcym S.r.l. previously Sorin Group Italia S.r.l.